Infectious Diseases Data Observatory and WWARN 330d ago

A one-hour webinar with presentations and an expert discussion: • Dr Rob Commons, Menzies School of Health Research, on 8AQ efficacy in clinical trials • Dr Alison Roth, Walter Reed Army Institute of Research, on laboratory studies assessing hypnozoitocidal activity • Dr James Watson, Oxford University Clinical Research Unit, on the reassessment of tafenoquine pharmacometrics • Discussion chaired by Dr Chau Nguyen Hoang, Oxford University Clinical Research Unit, and Professor Sir Nicholas White, Mahidol Oxford Research Unit About this event Large individual patient data meta-analyses show that the dosing of the 8-aminoquinoline drugs primaquine and tafenoquine could be substantially improved. These analyses include the majority of all studied vivax malaria patients who received 8-aminoquinoline drugs over the last 20 years. Laboratory work confirms these findings and provides important new information on the mechanism of action of these essential medicines. Please note, this video has not been fully subtitled.